Supplemental Material: Hydroxylated Metabolites of Polybrominated Diphenyl Ethers (PBDEs) in Human Blood Samples from the United States

نویسندگان

  • Xinghua Qiu
  • Robert M. Bigsby
  • Ronald A. Hites
چکیده

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منابع مشابه

Hydroxylated Metabolites of Polybrominated Diphenyl Ethers in Human Blood Samples from the United States

BACKGROUND A previous study from our laboratory showed that polybrominated diphenyl ethers (PBDEs) were metabolized to hydroxylated PBDEs (HO-PBDEs) in mice and that para-HO-PBDEs were the most abundant and, potentially, the most toxic metabolites. OBJECTIVE The goal of this study was to determine the concentrations of HO-PBDEs in blood from pregnant women, who had not been intentionally or o...

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Polybrominated Diphenyl Ethers (PBDEs) and Bioaccumulative Hydroxylated PBDE Metabolites in Young Humans from Managua, Nicaragua

OBJECTIVE Our aim was to investigate exposure to polybrominated diphenyl ethers (PBDEs) in a young urban population in a developing country, with focus on potentially highly exposed children working informally as scrap scavengers at a large municipal waste disposal site. We also set out to investigate whether hydroxylated metabolites, which not hitherto have been found retained in humans, could...

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Measurement of Polybrominated Diphenyl Ethers and Metabolites in Mouse Plasma after Exposure to a Commercial Pentabromodiphenyl Ether Mixture

BACKGROUND Previous studies have shown that polybrominated diphenyl ethers (PBDEs) behave as weak estrogens in animal and cell culture bioassays. In vivo metabolites of PBDEs are suspected to cause these effects. OBJECTIVES To identify candidate metabolites, mouse plasma samples were collected after continuous oral and subcutaneous exposure to DE-71, a widely used commercial pentabromodipheny...

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Levels and distribution of methoxylated and hydroxylated polybrominated diphenyl ethers in plant and soil samples surrounding a seafood processing factory and a seafood market.

Polybrominated diphenyl ethers (PBDEs) along with hydroxylated polybrominated diphenyl ethers (OH-PBDEs) and methoxylated polybrominated diphenyl ethers (MeO-PBDEs) were found in plant and soil samples collected surrounding a seafood processing factory and a seafood market in China. The profiles of MeO-PBDE congeners were different between seafood processing factory and seafood market. The dete...

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Polybrominated diphenyl ethers in maternal and fetal blood samples.

Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants in consumer goods, such as plastics, electronics, textiles, and construction material. PBDEs have been found in human milk, fat, and blood samples. Rodent studies indicate that PBDEs may be detrimental to neurodevelopment, possibly by lowering thyroid hormone concentrations in blood. In the present study, we determined c...

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تاریخ انتشار 2008