Regioselective synthesis of oxepinones and azepinones by gold-catalyzed cycloisomerization of functionalyzed cyclopropyl alkynes.
نویسندگان
چکیده
A regioselective synthesis of oxepinones and azepinones in good to excellent yields from alkynylcyclopropanecarboxylic acid derivatives is described. This novel cycloisomerization cascade process consists of a nucleophilic addition followed by a cyclopropane ring-opening, where both donor and acceptor groups are required as substituents of the cyclopropane ring.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 95 شماره
صفحات -
تاریخ انتشار 2013