Ubiquitin-like modifiers.

Erratum: The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers

A universal strategy for proteomic studies of SUMO and other ubiquitin-like modifiers.

Post-translational modification by the conjugation of small ubiquitin-like modifiers is an essential mechanism to affect protein function. Currently, only a limited number of substrates are known for most of these modifiers, thus limiting our knowledge of their role and relevance for cellular physiology. Here, we report the development of a universal strategy for proteomic studies of ubiquitin-...

Ubiquitin-like modifiers and their deconjugating enzymes in medically important parasitic protozoa.

Protein modification by ubiquitin and ubiquitin-like proteins is one of the most complex and intensely studied mechanisms of posttranslational protein regulation in eukaryotes. Conjugation of the 76-amino-acid protein ubiquitin is first and foremost a signal for targeting proteins to the proteasome for degradation, but evidence that ubiquitin also plays diverse roles in the regulation of numero...

Erratum: The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers

[This corrects the article on p. 105 in vol. 7, PMID: 27379156.].

The Role of Ubiquitin and Ubiquitin-Like Modification Systems in Papillomavirus Biology

Human papillomaviruses (HPVs) are small DNA viruses that are important etiological agents of a spectrum of human skin lesions from benign to malignant. Because of their limited genome coding capacity they express only a small number of proteins, only one of which has enzymatic activity. Additionally, the HPV productive life cycle is intimately tied to the epithelial differentiation program and ...