Exercise and Endogenous Opiates
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Exercise and Endogenous Opiates
The discovery of endogenous opiates in 1975 (1) generated considerable research concerning the effects of exercise on the release of these peptides, particularly on -endorphin, which represents the main focus of this chapter. Previous research considered changes in peripheral blood concentrations induced by different modes of physical activity, influences of training status on the secretion of ...
متن کامل2 Exercise and Endogenous Opiates
The discovery of endogenous opiates in 1975 (1) generated considerable research concerning the effects of exercise on the release of these peptides, particularly on -endorphin, which represents the main focus of this chapter. Previous research considered changes in peripheral blood concentrations induced by different modes of physical activity, influences of training status on the secretion of ...
متن کاملThe role of endogenous opiates in thermal regulation of the body during exercise.
Naloxone abolished the rise in body temperature seen after bicycle ergometer tests performed by 10 healthy men. This suggests that endogenous opiates play a part in thermal regulation during muscular exercise.
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The effect of repetitive electrical field stimulation and the response of the guinea-pig and rat ileal longitudinal muscle to single pulse stimulations was examined. Single pulse field stimulation produced twitch contraction which was inhibited by repetitive field stimulation (10 Hz, 40V, 0.5 msec for 5 m). This inhibition was largely, though never completely, reversed by naloxone. Contrac...
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Naltrexone HCl, a long-acting opiate receptor blocker was administered to female hamsters at two doses, 10 and 20 mg/kg, IP prior to 12 hr of nocturnal running or every 12 hr during access to hypothalamic self-stimulation to determine whether endogenous opiates played a role in either of these two motivated behaviors. Naltrexone suppressed total running activity and speed, and caused an increas...
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