Use and Abuse of Ergot in Obstetrics
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چکیده
to the administration of ergot during labour include: firstly, its possible foeticidal effects; secondly, the probability of giving rise to such irregular uterine action as may occasion subsequent retention of* the placenta; and thirdly, the direct tonic effect on the maternal system that has been attributed to this drug. From a study of 150 obstetric cases in which ergot was used, he comes to the conclusion that many of the
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First record of Epicoccum andropogonis growing on Paspalum dilatatum ergot in Iran
Paspalum dilatatum spikelets with ergot symptoms were collected from Rice Research Institute of Iran in Rasht, Guilan province during the fall of 2018. Ergot symptoms usually are caused by different Claviceps species on grasses. Sclerotia of ergot were globular in shape, black in color and irregularly roughened on the surface that resembles a brain. Different fungi were isolat...
متن کاملHistorical View on Ergot Alkaloids
A short survey of the history of ergot, of the original and, for a long time, only source of ergot alkaloids, is given. Once a dreaded poison, ergot has changed its role over the centuries to become a rich treasure house of valuable pharmaceuticals. In the Middle Ages it was the cause of epidemics of ergotism, which cost tens of thousands of people their lives. Ergot was first mentioned by the ...
متن کاملHistory of ergot alkaloids from ergotism to ergometrine.
Epidemics of ergotism occurred frequently in the Middle Ages. They were a source of inspiration for artists and were popularly known as 'St. Anthony's Fire', resulting in gangrene, neurological diseases and death. It was caused by eating rye bread contaminated with the fungus claviceps purpurea. In 1582 it was described that a delivery could be hastened by administering a few spurs of the secal...
متن کاملJohn Chassar Moir (1900-1977) and the discovery of ergometrine.
Chassar Moir led the research in the early 1930s that resulted in the discovery and identification of ergometrine, the active water soluble component of ergot of rye. Its use in preventing and controlling postpartum haemorrhage has saved countless lives in the years since. As professor of obstetrics and gynaecology in Oxford, he achieved distinction for his repair of vesicovaginal fistulae.
متن کاملClassic illustrations: From St. Anthony's fire to ergometrine (Ergonovine).
Time I " minutes Fig. 1. Figure taken from: Moir, C. (1932): The action of ergot preparations on the puerperal uterus. Bnt. In the Middle Ages St. Anthony ministered to those suffering the torments of intense burning and gangrene of the fingers and toes. It was clearly a painful condition graphically described as St. Anthony's fire and was eventually related to 'black' bread made from rye conta...
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