The role of inflammation in secondary cardiac dysfunction following trauma
نویسندگان
چکیده
Background Recent evidence supports the existence of a trauma induced secondary cardiac injury (TISCI) that is associated with poor clinical outcome [1]. Cardiac dysfunction has been demonstrated as early as 30mins after injury and is characterised by reduced contractility that is unresponsive to increased perfusion and preload [2].Inflammation is implicated as a key aetiological factor [1,3]. This review aims to evaluate current knowledge on cardiac inflammation after trauma and highlight mechanisms for future study.
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