P90 - Comparing the accuracy of skin prick tests to fresh milk or cow’s milk solution in predicting challenge outcomes
نویسندگان
چکیده
Introduction Allergy to cow’s milk is the most common allergy found in infants and young children. The estimated prevalence of milk allergy is 2-7.5% (Vandenplas) and the variability relates to diagnosis methods used and services available in any given demographic area. Skin prick tests (SPTs) are a well established and widely used method of allergy testing for cow’s milk. Many clinics use commercially available solutions in their clinics with the use of some fresh foods but there has been limited research available comparing the accuracy of these solutions compared to fresh foods and a literature search carried out in August 2012 only found 1 paper by Mauro et al. who looked into this. At the Royal Free Hospital, London UK, we introduced fresh milk SPTs alongside the use of solution in August 2011 to aid our decision making in these children.
منابع مشابه
Allergy to all mammalian Bovidae proteins but cow's milk in a child.
Cross reactivity between mammalian proteins (cow, goat, ewe, buffalo) has been previously described in both in vitro and in vivo studies. The highest homologies are observed between the milk proteins from cows and other Bovidae, being on average 96.1% for buffalo, 91.1% for ewe, and 87.6% for goat. Lower sequence similarities are associated with proteins contained in milks from Suidae (pigs and...
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Cow’s milk protein allergy (CMPA) is a common condition present in approximately 2-7.5% of children. The diagnosis is usually made in the first 12 months of life by taking a thorough clinical history and by performing confirmatory special investigations. These may include skin-prick tests, blood tests and an oral food challenge, which remains the gold standard investigation. Allergic reactions ...
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