1 Lappaol F , a novel anticancer agent isolated from plant Arctium Lappa
نویسندگان
چکیده
Correspondence: Ying Huang, M.D., Ph.D. Department of Pharmacology, State University of New York, Upstate Medical University 750 E. Adams Street Syracuse, New York 13210, USA. Email: [email protected] CoCorrespondence: Yingjie Hu, Ph.D. Laboratory of Chinese Herbal Drug Discovery, Tropical Medicine Institute, Guangzhou University of Chinese Medicine, 12 Jichang Road, Guangzhou 510405, China. E-mail: [email protected]
منابع مشابه
Small Molecule Therapeutics Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L
In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, fromplantArctiumLappaL. Lappaol F suppressed cancer cell growth in a timeanddose-dependent manner inhumancancer cell lines of various tissue types.We found thatLappaol F inducedG1 andG2 cell-cycle arrest, which was associated with strong induction of p21 and p27 and reduction of...
متن کاملLappaol F, a novel anticancer agent isolated from plant arctium Lappa L.
In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, from plant Arctium Lappa L. Lappaol F suppressed cancer cell growth in a time- and dose-dependent manner in human cancer cell lines of various tissue types. We found that Lappaol F induced G(1) and G(2) cell-cycle arrest, which was associated with strong induction of p21 and p27...
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