Further studies on the effects of pituitary growth hormone (STH) on C3H mice bearing a transplanted mammary adenocarcinoma.

The administration of pituitary growth hor mone (STH) to C3H mice bearing transplanted mammary adenocarcinoma has been shown to cause an increase in the tumor and animal weights when the mice were sacrificed at the end of a 27day injection period (5). It was also observed that the animals receiving STH appeared generally healthier than did their respective controls at the time they were sacrificed. In view of these interesting observations it ap peared desirable to study the effect of prolonged administration of STH (2, 3) on survival time, tumor weight, and body growth in C3H mice bearing transplanted mammary tumors.