New cytotoxic naphthopyrane derivatives from Adenaria floribunda.

نویسندگان

  • Ahmed A Hussein
  • Icela Barberena
  • Todd L Capson
  • Thomas A Kursar
  • Phyllis D Coley
  • Pablo N Solis
  • Mahabir P Gupta
چکیده

Bioassay-guided fractionation of an EtOAc/MeOH extract of Adenaria floribunda young leaves using MCF-7, H-460, and SF-268 cancer cell lines yielded four new active compounds named adenaflorins A-D (1-4). Their chemical structures were determined by spectroscopic means. Adenaflorin A (1) was the most cytotoxic.

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عنوان ژورنال:
  • Journal of natural products

دوره 67 3  شماره 

صفحات  -

تاریخ انتشار 2004