Antibodies for CFTR studies.

نویسندگان

  • Filipa Mendes
  • Carlos M Farinha
  • Mónica Roxo-Rosa
  • Pascale Fanen
  • Aleksander Edelman
  • Robert Dormer
  • Margaret McPherson
  • Heather Davidson
  • Edith Puchelle
  • Hugo De Jonge
  • Ghanshyam D Heda
  • Martina Gentzsch
  • Gergely Lukacs
  • Deborah Penque
  • Margarida D Amaral
چکیده

For most expression studies focusing on the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, sensitive and specific antibodies (Abs) are critically needed. Several Abs have been produced commercially or by research laboratories for CFTR detection in both cell lines with heterologous or endogenous expression and native cells/tissues. Here, we review the applicability of most Abs currently in use in CF research for the biochemical and/or immunocytochemical detection of CFTR.

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عنوان ژورنال:
  • Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

دوره 3 Suppl 2  شماره 

صفحات  -

تاریخ انتشار 2004