Serum folate by two methods in pregnant women carrying fetuses with neural tube defects.
نویسندگان
چکیده
Carrying Fetuses with Neural Tube Defects, Gizele Thame, Elvira Maria Guerra-Shinohara, and Antonio Fernandes Moron ( Departamento de Saúde Materno-Infantil, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo-SP, Brazil CEP 05054-010; 2 Seção de Hematologia, Instituto Adolfo Lutz, São Paulo-SP, Brazil; 3 Departamento de Análises Clı́nicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo-SP, Brazil CEP 05508-900; 4 Setor de Medicina Fetal da Disciplina de Obstetrı́cia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo-SP, Brazil CEP 0437-002; address correspondence to this author at: Rua Aibi, 146, São Paulo-SP, Brazil CEP 05054-010; fax 55-11-5083-5409, e-mail gizelethame@ hotmail.com)
منابع مشابه
Evaluation of maternal serum folate, vitamin B12, and homocysteine levels andfactor V Leiden, factor II g.20210G>A, and MTHFR variations in prenatallydiagnosed neural tube defects.
BACKGROUND/AIM Neural tube defects (NTDs) are common congenital malformations that develop as a result of interactions between several genes and environmental factors. Many factors have been investigated in order to understand the etiology of NTDs, and many studies have identified folate intake as a common contributing factor. The exact etiology of the disease is still unknown. MATERIALS AND ...
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BACKGROUND Neural tube defects related to polygenic disorders are the second most common birth defects in the world, but no molecular biologic tests are available to analyze the genes involved in the pathomechanism of these disorders. We explored the use of routinely collected amniotic fluid to characterize the differential gene expression profiles of polygenic disorders. METHODS We used olig...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 48 7 شماره
صفحات -
تاریخ انتشار 2002