Fatal vascular access hemorrhage: reducing the odds.

Halting hemorrhage with self-propelling particles and local drug delivery

Approaches to locally deliver drugs to specific regions of the body are being developed for many clinical applications, including treating hemorrhage. Increasing the concentration of therapeutic coagulants in areas where clots are forming and growing can be achieved by directing them to the injury, such as with catheters or external delivery devices, or by systemically administering therapeutic...

Endovascular stroke therapy: tirofiban is associated with risk of fatal intracerebral hemorrhage and poor outcome.

BACKGROUND AND PURPOSE To investigate the relationship between severe bleeding complications and outcome after mechanical thrombectomy with or without glycoprotein-IIb/IIIa inhibitor tirofiban treatment. METHODS The study included prospectively collected data of consecutive patients with acute ischemic stroke in whom mechanical thrombectomy was perfomed in the years 2006 to 2011. RESULTS Of...

Systematic review of long term anticoagulation or antiplatelet treatment in patients with non-rheumatic atrial fibrillation.

OBJECTIVE To examine the benefits and risks of long term anticoagulation (warfarin) compared with antiplatelet treatment (aspirin/indobufen) [corrected] in patients with non-rheumatic atrial fibrillation. METHODS Meta-analysis of randomised controlled trials from Cochrane library, Medline, Embase, Cinhal, and Sigle from 1966 to December 1999. Odds ratios (95% confidence intervals) calculated ...

Dieulafoy's vascular malformation as a cause of large intestinal bleeding.

Four cases of Dieulafoy's vascular malformation of the caecum are reported. Three were associated with massive large bowel haemorrhage, one of which was fatal. The remaining case had a calibre persistent submucosal artery within the caecum that was found incidentally in a resection specimen. This vascular malformation should be considered when dealing with specimens resected for massive lower g...

Retrograde cerebral perfusion: report of a fatal complication from a subarachnoid venous hemorrhage during thoracoabdominal aortic surgery.