Giant iridodialysis with wound dehiscence following penetrating keratoplasty: an ocular emergency.

Urkude JS, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220753 Description Wound dehiscence is a known complication of keratoplasty which can occur even many years following the surgery. Usually trivial trauma is the causative factor for wound dehiscence, but spontaneous dehiscence has also been reported in the literature. A 45-year-old man presented with sudden loss of vision in the left eye following a blunt trauma. History revealed penetrating keratoplasty in the left eye for perforated corneal ulcer 2 years ago. On examination, visual acuity was hand movement close to face in the left eye and right eye being within normal limits with 20/20 visual acuity. Slit-lamp biomicroscopic examination showed broken monofilament nylon sutures leading to superior 6 clock hours (09:00 to 03:00 clock hours) of wound dehiscence, with corresponding 6 clock hours of giant iridodialysis prolapsing anteriorly (figure 1). The lens was completely extruded along with vitreous at the wound. Based on the relevant history and clinical findings, a diagnosis of giant iridodialysis secondary to wound dehiscence following blunt trauma was made. As the injury was more than 48 hours old, the prolapsed iris tissue was abscissed along with limited anterior vitrectomy followed by resuturing of the same graft to the host bed under general anaesthesia. First postoperative day showed a well-apposed graft-host junction (GHJ), with a well-formed anterior chamber (figure 2). At the end of 5 months, the patient is without any complications, and the best-corrected visual acuity is 20/80 with a well-attached retina in presence of healthy optic disc and macula. Wound dehiscence is one of the most dreaded complications following keratoplasty. GHJ healing occurs mainly at the level of endothelium and epithelium. Because of this, full thickness grafts are more prone for dehiscence as compared with lamellar grafts in which Descemet membrane and endothelium remain untouched giving extra support to transplanted cornea. The location for wound dehiscence is seen almost equal in all quadrants; in our case, the large dehiscence was located in the superior quadrant. Giant iridodialysis associated with wound dehiscence is rarely encountered in clinical practice. In this case, it was a large iridodialysis prolapsing out of the anterior chamber which was taken care of. The final outcome in these cases depends on many factors like time elapsed between injury Giant iridodialysis with wound dehiscence following penetrating keratoplasty: an ocular emergency