Integration on Noncoding RNA Studies
نویسندگان
چکیده
Recent genome-wide studies revealed that the human genome encodes over 10,000 long non-coding RNAs (lncRNAs) with little protein-coding capacity. Growing evidence suggests that many lncRNAs may have important functions in complex diseases and are potentially a new class of therapeutic targets for treating complex disease. In contrast to the fast pace of cataloguing lncRNAs in the human genome, the function of the vast majority of lncRNAs remain unknown. In this chapter, we described data integration strategies for identifying lncRNA that are associated with cancer subtypes and clinical prognosis, and predicted those that are potential drivers of cancer progression.
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تاریخ انتشار 2016