Efficacy Enhanced by an Anti-IL-2 mAb IL-2 In Vivo Activities and Antitumor
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منابع مشابه
IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb.
IL-2 is a potent immunostimulant and has been tested for clinical use, including in immunotherapy for cancers and HIV infection. Here we show that a widely used neutralizing anti-murine IL-2 mAb (S4B6) exhibits unexpected activities that enhance the treatment effects of IL-2 in vivo. Coinjection of the anti-IL-2 mAb with a plasmid carrying murine IL-2 cDNA significantly increased the serum IL-2...
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