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Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (X.L., J.L., S.L., Y.Z., X.W., C.Z., M.H.) Kidney Transplant Department, Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China (Q.F. , H.W., J.L., C.W.) Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China (S.L.) School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China (Y.Z.) This article has not been copyedited and formatted. The final version may differ from this version. DMD Fast Forward. Published on January 13, 2015 as DOI: 10.1124/dmd.114.062117