One hundred years of poliovirus pathogenesis.

Immunity to poliovirus serotypes in children population of selected communities in South-west, Nigeria.

BACKGROUND Poliovirus outbreaks are still reported in Nigeria despite renewed efforts to improve vaccine coverage, thus suggesting the existence of susceptible hosts. Also, there is anecdotal evidence of variation in vaccine coverage by region and specifically between urban and rural communities. Consequently, this study assessed neutralizing antibodies to poliovirus serotypes among children in...

Genomic Analysis of Vaccine-Like Poliovirus Isolates from Stool Specimens of Acute Flaccid Paralysis Cases with Residual Paralysis during the Years 1380-1381 in Iran

Poliovirus Particles do not Form in Preinfected Cells with Reovirus

Background and Aims: Inhibition of viral growth in coinfected cells with two different viruses has been described. This phenomenon known as viral interference can occur in several virus host systems such as interference of enterovirus infection on poliovirus vaccine strains. In this study we superinfected reovirus infected HeLa cells with poliovirus to determine if poliovirus can replicate in s...

Alarm of Circulating Wild Poliovirus and Of Vaccine-Derived Poliovirus in Middle East Countries as a Potential Risk for Re-Emerging of Polio in Iran

     Poliomyelitis is a highly infectious viral disease which is mainly transmitted via contaminated food and drinking water by human feces, especially in situations of poor hygiene and sanitation (1). This disease is caused by 3 types of wild poliovirus (WPV) (types 1, 2 and 3), and immunity against one type does not create immunity against other types. In our country according National Immuni...

David Bodian's contribution to the development of poliovirus vaccine.

David Bodian spent almost his whole scientific career (1942–1983) at the Johns Hopkins University, first in the Department of Epidemiology at the School of Hygiene and Public Health and then in the Department of Anatomy at the School of Medicine. Arguably, his most important research contribution was the elucidation of the pathogenesis of poliomyelitis—a contribution that played a major role in...