Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide.

Synthesis of polyvinyl pyridine/C60 conjugates in supercritical carbon dioxide*

In the present investigation efforts have been made to synthesis polyvinyl pyridine (PvPy) /C60 conjugates through 2, 2-azobisisobutyronitrile (AIBN) initiated insitu polymerization of PvPy in scCO2.The process of synthesis was monitored under different reaction conditions ranging 1200-1800psi, 60-90 oC over 6 hours. The progress of polymerization was monitored rheoviscometrically. The concentr...

Continuous Synthesis of Oleyl Oleate in Supercritical Carbon Dioxide using Solid p-Toluenesulfonic Acid as Catalyst

Supercritical carbon dioxide (SC-CO2) was used as solvent to synthesize oleyl oleate as an analog of Jojoba oil from oleic acid and oleyl alcohol with high conversion (100%) of the acid into ester in a short time of 100 min. Utilizing a low cost solid catalyst, p-toluenesulfonic acid monohydrate (PTSA), the esterification reaction was performed, without any prior preparation step...

CO2 as an Oxygen Source for Polysiloxanes – Preparation, Crystal Structure and Thermal Decomposition of Two Novel Silylcarbamates

Diaminosilanes (CH3)2Si(NHR)2 1a, b are obtained from dichlorodimethylsilane and primary amines (R = n-hexyl, iso-propyl) in good yields. Bis-insertion of CO2 into the Si–N bonds of the aminosilanes quantitatively gives the silylcarbamates (CH3)2Si(OCONHR)2, 2a, b. Oligoand polydimethylsiloxanes 3a, b as well as N,N′-substituted ureas CO(NHR)2 4a, b are formed upon heating the silylcarbamates 2...

Measurement and Correlation of Ibuprofen in Supercritical Carbon Dioxide Using Stryjek and Vera EOS

Solubility Prediction of Drugs in Supercritical Carbon Dioxide Using Artificial Neural Network

The descriptors computed by HyperChem® software were employed to represent the solubility of 40 drug molecules in supercritical carbon dioxide using an artificial neural network with the architecture of 15-4-1. The accuracy of the proposed method was evaluated by computing average of absolute error (AE) of calculated and experimental logarithm of solubilities. The AE (±SD) of data sets was 0.4 ...