The Novel Application of Chiral -Ethylphenyl Amine Tartaric Acid Salts- Cyanosilylation of Prochiral Aldehydes
نویسندگان
چکیده
The -ethylphenylamine tartaric acid salts 1a-1d were synthesized from R-(+)/S-(-)-ethylphenylamine by reacting with (2S,3S)-(+)/(2R,3R)-(-) dihydrobutanedioic acid. They were used as the catalysts in cyanosilylation of prochiral aldehydes to give the corresponding cyanohydrin trimethylsilyl ethers in moderate conversion at room temperature.
منابع مشابه
The Cyanation of Prochiral Aldehydes with Chiral Copper Complexes of R-(+)/S-(-) -α-Ethylphenyl Amine in Methanol
Interesting and unexpected results on the cyanation of prochiral aldehydes catalyzed by chiral copper complexes of R-(+)/(S)-(-) α-ethylphenyl amine (I/II) in anhydrous methanol are presented. The cyanation reaction with chiral copper complexes of R-(+)/S-(-) α-ethylphenyl amines, acetols in methanol perform to afford a series of chiral products such as amines and acetonitriles (compounds 4-6, ...
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