Synthesis and properties of a Cu(II) complexing pyrazole ligandoside in DNA.

نویسندگان

  • M Su
  • María Tomás-Gamasa
  • S Serdjukow
  • P Mayer
  • T Carell
چکیده

The development of metal base pairs is of immense importance for the construction of DNA nanostructures. Here we report the synthesis of a biaryl pyrazole-phenol nucleoside that forms in DNA a stable self-pair upon complexation of a Cu(II) ion. A sequence with five consecutive pyrazole nucleotides allows the complexation of five Cu(II) ions in a row.

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عنوان ژورنال:
  • Chemical communications

دوره 50 4  شماره 

صفحات  -

تاریخ انتشار 2014