Malignant ventricular arrhythmias in patients with chronic myocardial infarction and predictive value of iron-sensitive cardiac magnetic resonance imaging
نویسندگان
چکیده
Background Recent studies in canines have shown that focal iron depositions within chronic scar tissue influences the electrical behavior of infarcted hearts. Further, T2weighted CMR of post-mortem sudden cardiac death (SCD) victims with chronic myocardial infarction (CMI) have consistently demonstrated regions of signal loss within the CMI territories. To date, the link between the post-infarction iron depositions and malignant ventricular arrhythmias (mVA) in patients with CMI is not known. The aim of this study was to determine the incremental prognostic value of hypointense cores (HIC) identified within CMI using a potentially iron-sensitive CMR approach at 3.0T for the prediction of mVA.
منابع مشابه
Iron-Sensitive Cardiac Magnetic Resonance Imaging for Prediction of Ventricular Arrhythmia Risk in Patients With Chronic Myocardial Infarction: Early Evidence.
BACKGROUND Recent canines studies have shown that iron deposition within chronic myocardial infarction (CMI) influences the electric behavior of the heart. To date, the link between the iron deposition and malignant ventricular arrhythmias in humans with CMI is unknown. METHODS AND RESULTS Patients with CMI (n=94) who underwent late-gadolinium-enhanced cardiac magnetic resonance imaging befor...
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