The Production of Oriental Sore in Man by Flagellate Culture of Leishmania Tropica *Being a paper read at the Indian Science Congress, Lahore, in January, 1927.

نویسنده

  • Ganapati Panja
چکیده

a building contractor by occupation. The back of the volunteer's shoulder was selected for inoculation, as it was under the clothes and covered by the shirt. The skin was sterilised with tincture of iodine and washed with absolute alcohol. A hypodermic Record syringe was sterilised in olive oil at 140?C, cooled, and then filled with 1 c.c. of the culture of Leishmania tropica from the water of condensation of the NNN medium. This fl'uid was then injected intracntaneously over an area of about fth of an inch diameter on 15th August, 1925. A week later the man was examined and the inoculated area was found normal in appearance.' A second injection was given as above at the same spot with a week-old culture. A very small nodule developed in about three weeks at the site of inoculation; otherwise the man was in perfect health. The nodule persisted, but gave no trouble except that it was slightly itchy. The volunteer went to Kathiawar on 1st May, 1926, i.e., about 8^ months after the inoculation. The nodule enlarged and ulcerated after a further 3 to 4 months, i.e., a year later, when in Kathiawar. The man then

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عنوان ژورنال:

دوره 62  شماره 

صفحات  -

تاریخ انتشار 2016