Sofosbuvir: an antiviral drug with potential efficacy against Zika infection.
نویسندگان
چکیده
منابع مشابه
Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes neurological disorders during fetal development and in adulthood, antiviral drugs are necessary. Sofosbuvir is clinically approved for use against HCV and targets the protein that is most conserved among the members of ...
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Although Zika virus (ZIKV) infection is often asymptomatic, in some cases, it can lead to birth defects in newborns or serious neurologic complications in adults. However, little is known about the interplay between immune and neural cells that could contribute to the ZIKV pathology. To understand the mechanisms at play during infection and the antiviral immune response, we focused on neural pr...
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ورودعنوان ژورنال:
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
دوره 55 شماره
صفحات -
تاریخ انتشار 2017