Toluidine blue: A review of its chemistry and clinical utility
نویسندگان
چکیده
Toluidine blue is a basic thiazine metachromatic dye with high affinity for acidic tissue components, thereby staining tissues rich in DNA and RNA. It has found wide applications both as vital staining in living tissues and as a special stain owing to its metachromatic property. Toluidine blue has been used in vivo to identify dysplasia and carcinoma of the oral cavity. Use of toluidine blue in tissue sections is done with the aim to highlight components, such as mast cells granules, mucins, and cartilage. This article provides an overview on chemistry, technique, and the various applications of toluidine blue.
منابع مشابه
Flow Injection Spectrophotometric Determination of Sulphide by Catalytic Reduction of Toluidine Blue
Sulphide was determined spectrophotometrically at 628 nm and pH 6.7 based on its catalytic reduction of toluidine blue in the presence of Se(IV) using a flow injection system. After optimization of the measuring conditions the calibration curve was found linear up to 25 mg/mL and the detection limit was 0.3 mg/mL (30 mL injections). The ...
متن کاملPhotodynamic inactivation effect of methylene blue and toluidine blue O on ATCC Escherichia coli and clinical isolate of multidrug-resistant Escherichia coli
متن کامل
Magnetic Multi-Walled Carbon Nanotube as an Adsorbent for Toluidine Blue O Removal from Aqueous Solution
Toluidine Blue O (TBO) is a cationic dye which is extensively used in the industries. In the present paper a simple and efficient wet chemical method was introduced for removal of TBO from waste aqueous solution. Magnetic multi-walled carbon nanotubes were synthesized using commercially available multi-wall carbon nanotubes and magnetic iron oxide nanoparticles which were examined for removal o...
متن کاملCatalytic Spectrophotometric Determination of Traces of Tellurium (IV)
A Simple, rapid and sensitive method has been developed for determination of trances of tellurium (VI) (0.096-1.250 mg/mL) based on its catalytic effect on the reduction reaction of toluidine blue by sulfide ion at pH 4. The reaction is monitored spectrophotometrically by measuring the decrease in absorbance of the dyestuff at 628 nm by the fixed time method. The detection...
متن کاملHisto-cytological Correlation of Oral Premalignant and Malignant Lesion in Specimens from Toluidine Blue Stained Buccal Mucosa
Objective behind the study was to assess the efficacy of Toluidine Blue (TB) mouth rinse in the detection of neoplasia in oral cavity and to evaluate its usefulness in high risk groups. Correlation of the results of scrape cytology smear and histopathology of biopsy taken from the TB stained area was also done. This prospective study was carried out on 85 cases of suspected oral lesions. Comple...
متن کامل