Increased sensitivity to endothelial nitric oxide/NO contributes to arterial normotension in mice with vascular smooth muscle - selective deletion of the ANP-receptor
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چکیده
Running title: Vascular interactions between ANP and NO Classification: Biological Sciences, Physiology Manuscript information: 21 pages, 6 figures; abstract with 245 words, 5151 words in total. Abbreviations footnote: ANP, atrial natriuretic peptide; CNP, C-type natriuretic peptide; NO, nitric oxide; GC-A, guanylyl cyclase-A; sGC, soluble guanylyl cyclase; PKG I, cGMPdependent Protein Kinase I; SMC, smooth muscle cells
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IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.
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