Effects of Glucose 6-Phosphate Dehydrogenase Deficiency on the Metabolic 1 and Cardiac Responses to Obesogenic or High Fructose Diets
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چکیده
3 By: Peter A. Hecker, Rudo F. Mapanga, Charlene P. Kimar, Rogerio F. Ribeiro Jr, 4 Bethany H. Brown, Kelly A. O’Connell, James W. Cox, Kadambari C. Shekar, 5 Girma Asemu, M. Faadiel Essop, and William C. Stanley 6 From: Division of Cardiology and Department of Medicine, University of Maryland, 7 Baltimore, MD, USA 8 Cardio-Metabolic Research Group, Department of Physiological Sciences, Stellenbosch 9 University, Stellenbosch, South Africa 10 Correspondence: William C. Stanley, Ph.D. 11 Professor, Division of Cardiology, Department of Medicine 12 University of Maryland-Baltimore 13 20 Penn Street, HSF2, Room S-022 14 Baltimore, MD 21201 15 Phone: 410-706-3585 16 Fax: 410-706-3583 17 Email: [email protected] 18 19 Word count: 10,731 20 Tables: 6 21 Figures: 7 22 Running Head: G6PD Deficiency and Diet-Induced Metabolic Syndrome 23 24 Articles in PresS. Am J Physiol Endocrinol Metab (July 24, 2012). doi:10.1152/ajpendo.00202.2012
منابع مشابه
Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common human enzymopathy that affects cellular redox status and may lower flux into nonoxidative pathways of glucose metabolism. Oxidative stress may worsen systemic glucose tolerance and cardiometabolic syndrome. We hypothesized that G6PD deficiency exacerbates diet-induced systemic metabolic dysfunction by increasing oxidative stress bu...
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The overall incidence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Iranian population is estimated around 10%-14.9%. G6PD deficiency is an X-linked disorder and 80% of donors are usually male. At present, donors’ blood is not routinely screened for G6PD deficiency in Iran blood bank where for detecting such enzyme deficiency, reliance is placed on pre-donation data. Thus, the G6PD ...
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