Carcinostatic action of polycarbonyl compounds and their derivatives. I. 3-Ethoxy-2-ketobutyraldehyde and related compounds.
نویسندگان
چکیده
Underwood and co-workers (27) recently re ported that a number of a-ketoaldehydes and closely related compounds were active against Newcastle disease virus (NJKD strain) and in fluenza virus (PR-8 strain) in embryonated eggs. These substances also had potent virus-inactivat ing effects in vitro. Underwood and Weed (28) found that glyoxal and methylglyoxal were active virucides in blood. Consequently, it seemed
منابع مشابه
Carcinostatic action of polycarbonyl compounds and their derivatives. III. Hydroxymethylglyoxal bis (guanylhydrazone).
The authors have previously noted the moder ate antileukemic effects of a-ketoaldehydes (2) and the considerably more potent antileukemic effects of glyoxal bis(guanylhydrazone) and methylglyoxal bis(guanylhydrazone) (1). These com pounds and closely related drugs were also studied as inhibitors of Adenocarcinoma 755. Preliminary investigation indicated that hydroxymethylglyoxal bis(guanylhydra...
متن کاملCarcinostatic action of polycarbonyl compounds and their derivatives. II. Glyoxal bis (guanylhydrazone) and derivatives.
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متن کاملCarcinostatic action of polycarbonyl compounds and their derivatives. IV. Glyoxal bis (thiosemicarbazone) and derivatives.
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عنوان ژورنال:
- Cancer research
دوره 18 2 شماره
صفحات -
تاریخ انتشار 1958