Neurobiology of Disease The Role of Brain-Derived Neurotrophic Factor (BDNF) in the Development of Neurogenic Detrusor Overactivity (NDO)
نویسندگان
چکیده
Bárbara Frias,1,2 João Santos,1 Marlene Morgado,3 Mónica Mendes Sousa,3 Susannah M.Y. Gray,6 Karen D. McCloskey,6 Shelley Allen,4 Francisco Cruz,2,5 and Célia Duarte Cruz1,2 1Department of Experimental Biology, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal, 2Translational NeuroUrology and 3Nerve Regeneration Group, IBMC–Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150-180 Porto, Portugal, 4Molecular Neurobiology Unit, University of Bristol, School of Clinical Sciences, BS10 5NB Bristol, United Kingdom, 5Department of Urology, Hospital de S. João, 4200-319 Porto, Portugal, and 6Centre for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, BT7 1 NN Belfast, United Kingdom
منابع مشابه
Role of Brain Derived Neurotrophic Factor (bdnf) in Neurogenic
1. Department of Experimental Biology, Faculty of Medicine of Porto, University of Porto, Portugal; IBMCInstituto de Biologia Molecular e Celular, Universidade do Porto, Portugal., 2. Molecular Neurobiology Unit, University of Bristol, CSSB, Dorothy Hodgkin Building, Bristol, UK, 3. Department of Urology, Hospital de S. João, Porto, Portugal; IBMCInstituto de Biologia Molecular e Celular, Unive...
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Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
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