Multiple ophthalmic abnormalities in an infant rhesus macaque (Macaca mulatta)

BACKGROUND A 4.5-month-old male colony-bred Indian rhesus macaque was presented for presumed trauma to the right eye. The globe was centrally distended 5 mm, with apparent hyphema and moderate to severe corneal edema. Surgical enucleation was performed. The initial histopathology report concluded chronic keratitis. Nearly 3 years later, a diagnosis of goniodysgenesis was made. The eye was sent to a veterinary ocular pathologist for definitive diagnosis. CONCLUSIONS Final conclusions were anterior segment and corneal defects. Based on the retinal pathology and optic nerve pathology, there was evidence of optic nerve atrophy, a recently described condition in macaques.