Requirement of Thymus (t) Lymphocytes for Resistance to Listeriosis

نویسندگان

  • F. C. Lane
  • E. R. Unanue
چکیده

Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if treated with anti-theta serum do not transfer resistance to Listeria. Hence, thymus (T) lymphocytes are involved in the resistance to infection with the facultative intracellular bacteria L. monocytogenes.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 135  شماره 

صفحات  -

تاریخ انتشار 1972