A history of the Arthritis Research Campaign Epidemiology Unit, 1954-2004.

نویسنده

  • A J Silman
چکیده

The founders of the Arthritis Research Campaign (arc) Epidemiology Unit were Kellgren and Lawrence. Their initial work was conducted in miners and then in the general population. They pioneered standardized methods of interview, examination and X-ray evaluation. They also played a key role in the early development of classification criteria for use in epidemiological surveys. The second director, Philip Wood, focused on understanding the impact of rheumatic diseases on the individual and on society. He was largely responsible for the International Classification of Impairments Disabilities and Handicaps. In the last 30 yrs, developments in statistics, computing and genetics have enabled the basic questions of disease aetiology to be re-examined. The third director, Alan Silman, took over in 1988. The Unit now has three research divisions: Genetics and Genomics, Outcome Studies and Population Surveys.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The epidemiology of osteoarthritis: Manchester and beyond.

The paper describes the contribution made to the understanding of the epidemiology of osteoarthritis by the Arthritis Research Campaign Epidemiology Unit. Kellgren and Lawrence defined the condition radiographically and produced the widely used Atlas of Standard Radiographs of Arthritis. They documented the age- and sex-specific prevalence of osteoarthritis. Based on studies in occupational gro...

متن کامل

Human Macrophage Migration Inhibitory Factor (mif): a Proven Immunomodulatory Cytokine?

HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF): A PROVEN IMMUNOMODULATORY CYTOKINE? Alex Kudrin‡, Martin Scott§, Steven Martin§, Chun-wa Chung§, Rachelle Donn¶¥, Andrew McMaster¥, Stuart Ellison¥, David Ray¶, Keith Ray‡, Michael Binks‡ From the ‡Department of Disease Biology, Rheumatology and Inflammation, GlaxoSmithKline, Stevenage, United Kingdom, SG1 2NY. §Discovery Research, GlaxoSmithK...

متن کامل

Epidemiology of Neonatal Cancer and its Correlation with Different Factors

Background: Tumors are among the main causes of neonatal intensive care unit (NICU) admission. We aimed to determine the frequency distributions and presentations of tumors in newborns admitted to the NICU of a children’s medical center. Methods: In this observational cross-sectional study, we reviewed medical records of 53 neonates admitted to the NICU of a children’s medical center during 20...

متن کامل

Looking back: developments in our understanding of the genetic epidemiology of rheumatoid arthritis over the last 50 years.

The contribution of the arc Epidemiology Unit over its 50-yr history to the study of the genetic epidemiology of rheumatoid arthritis (RA) has been reviewed. Early family and population based studies carried out by John Lawrence were important in establishing the role of both genetic and environmental factors in determining susceptibility to RA. More recently, under the leadership of Alan Silma...

متن کامل

Epidemiology and Clinical Features of Psoriasis Patients Admitted to A Dermatology Ward

Abstract Introduction: Psoriasis is a chronic, immune-mediated, inflammatory disease which affects primarily the skin and joints. It occurs worldwide, but its prevalence varies considerably between different regions of the world. Objective: To determine of epidemiologic aspects and clinical features of psoriasis among the patients admitted to a tertiary referral hospital. Materials and Metho...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Rheumatology

دوره 44 Suppl 4  شماره 

صفحات  -

تاریخ انتشار 2005