Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans.
نویسندگان
چکیده
Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their findings stress that atypical activity in the efferent auditory pathway may represent a shared substrate, as well as a potential therapeutic target, in tinnitus and hyperacusis.
منابع مشابه
Neuro Forum Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans
Sturm JJ, Weisz CJ. Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans. J Neurophysiol 114: 2551–2554, 2015. First published February 18, 2015; doi:10.1152/jn.00948.2014.—Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197–3208, 2014) demo...
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Atypical medial olivocochlear (MOC) feedback from brain stem to cochlea has been proposed to play a role in tinnitus, but even well-constructed tests of this idea have yielded inconsistent results. In the present study, it was hypothesized that low sound tolerance (mild to moderate hyperacusis), which can accompany tinnitus or occur on its own, might contribute to the inconsistency. Sound-level...
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OBJECTIVE Tinnitus may be caused by a lesion or dysfunction at any level of the auditory system. This study explores cochlear mechanics using otoacoustic emissions in patients with tinnitus after head injury, in whom there seems to be evidence to support dysfunction within the CNS. METHODS The study included 20 patients with tinnitus and other auditory symptoms, such as hyperacusis and diffic...
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ورودعنوان ژورنال:
- Journal of neurophysiology
دوره 114 5 شماره
صفحات -
تاریخ انتشار 2015