Myriocin, a new antifungal antibiotic from Myriococcum albomyces.

Elucidation of structure and stereochemistry of myriocin. A novel antifungal antibiotic.

بررسی فعالیت ضد قارچی اکتینومیست‌های جداشده از رسوبات بستر دریای مازندران

Background and purpose: Actinomycetes were always considered as a source of essential new antibiotic producers and secondary metabolite in pharmaceutical industries. This study aimed to isolate antibiotic producing actinomycetes from sediments of the Caspian Sea and investigate their potential as antifungal metabolites production. Materials and methods: Sediments of the Caspian Sea were collec...

Xanthoepocin, a new antibiotic from Penicillium simplicissimum IFO5762.

A new antifungal antibiotic xanthoepocin was isolated from the culture broth of Penicillium simplicissimum IFO5762. Xanthoepocin was obtained from the culture fluid by solvent extraction and chromatographic purification. It showed antibiotic activity against Gram-positive bacteria and yeasts.

Histidinomycin, a new antifungal antibiotic.

A new antifungal antibiotic named histidinomycin was isolated from the broth filtrate of a streptomycete, tentatively designated as isolate H 878-MY 1. Histidinomycin was purified as the monohydrochloride and the molecular formula was proposed to be C22H30N8O11.HCl. The antibiotic gave histidine by acid hydrolysis. Histidinomycin showed rather narrow antimicrobial spectrum for only few genera o...

Synerazol, a new antifungal antibiotic.

Synerazol, a new antifungal antibiotic, was isolated from cultured broth of Aspergillus fumigatus SANK 10588. The structure was determined based on NMR and mass spectral evidences. Synerazol was found to be a related substance to pseurotin A. Synerazol was active against Candida albicans and other fungi, and showed marked synergistic activity with azole-type antifungal agents.