Migraine pain--intracranial or extracranial?
نویسنده
چکیده
sensory neurons in the rat trigeminal ganglion. Brain Res. 2001;890:184-188. 11. Shields SD, Mazario J, Skinner K, Basbaum AI. Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons. Pain. 2007;131:8-20. 12. Hou M, Kanje M, Longmore J, Tajti J, Uddman R, Edvinsson L. 5-HT1B and 5-HT1D receptors in the human trigeminal ganglion: Co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase. Brain Res. 2001;909:112-120.
منابع مشابه
Role of the extracranial arteries in migraine headache: a review.
The pain of the migraine headache is often so debilitating that it severely compromises quality of life. The vascular component of the trigeminovascular system has been implicated in the pain mechanism. There is, however, debate as to whether the pain originates in the intracranial or extracranial vasculature or in both. In this article, evidence is presented to suggest that the extracranial ar...
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Over the years, there has been a considerable amount of controversy as to whether the vascular component of migraine pain arises from the intracranial or the extracranial vessels or both. Some have even questioned whether vasodilatation even plays a significant role in migraine pain and have described it as an unimportant epiphenomenon. In this review, evidence is presented that confirms (1) va...
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The pathogenesis of migraine pain has not yet been adequately explained and remains the subject of vigorous debate. Early studies by Harold Wolff and his associates on the extracranial terminal branches of the external carotid artery provided compelling evidence of their involvement in the evolution of migraine pain. They postulated that migraine pain emanates from dilated extracranial arteries...
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Dr. Young’s reply to my original letter in the April edition of Headache does not address the central issue. The sole object of my letter was to bring to the attention of the readers of Headache the fact that Wolff’s hard scientific evidence showing the involvement of the extracranial branches of the external carotid artery in the pain of migraine has been specifically and inexplicably excluded...
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Migraine headache is commonly associated with signs of exaggerated intracranial and extracranial mechanical sensitivities. Patients exhibiting signs of intracranial hypersensitivity testify that their headache throbs and that mundane physical activities that increase intracranial pressure (such as bending over or coughing) intensify the pain. Patients exhibiting signs of extracranial hypersensi...
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No definitive pathophysiology exists for migraine yet, nevertheless, many theories were postulated with the most ancient one being the vascular theory which was developed by H. Wolff during the 1940s [1]. According to Lauritzen, Wolff described migraine as a vasospastic disorder that is initiated by vasoconstriction in the cranial vasculature. The vasoconstriction is then followed by dilatation...
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ورودعنوان ژورنال:
- Headache
دوره 47 10 شماره
صفحات -
تاریخ انتشار 2007