IL-12– and IL-23–induced T helper cell subsets
نویسندگان
چکیده
Traditionally, CD4(+) T cells have been separated into two different subsets named T helper (Th)1 and Th2. A new IL-23-driven subset of Th cells called Th(IL-17) has now been described. The data suggest that IL-23 plays an important role in the differentiation of autoreactive pathogenic T cells. Whether these IL-23-induced Th(IL-17) cells are a unique subset or are related to other Th subsets is discussed.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 201 شماره
صفحات -
تاریخ انتشار 2005