Assessment of iron deposition in the heart in sickle cell patients using 3.0 Tesla cardiovascular magnetic resonance

نویسندگان

  • El-Sayed Ibrahim
  • Fauzia Rana
  • Kevin Johnson
  • Richard White
چکیده

This study investigates the role of 3.0T R2* imaging for measuring cardiac iron overload. Experiments were conducted on calibrated phantoms and sickle cell disease (SCD) patients. R2* imaging at 3.0T enabled assessment of wide range of iron concentrations. R2* values at 3.0T were about double of those at 1.5T. Myocardial R2* showed weak and strong correlations with hepatic R2* and serum ferritin, respectively. In conclusion, R2* imaging at 3.0T is promising technique for assessing cardiac iron overload in SCD with high sensitivity and reproducibility.

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2012