One-Sample Logrank Tests

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چکیده

Introduction This module computes the sample size and power of the one-sample logrank test which is used to compare the survival curve of a single treatment group to that of a historic control. Such is often the case in clinical phase-II trials with survival endpoints. Accrual time, follow-up time, and hazard rates are parameters that can be set. Several authors have presented sample size formulas for this situation. We have adopted those of Wu (2015) because his paper included an extensive simulation study that showed that his formulation is the most accurate.

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تاریخ انتشار 2015