Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives.
نویسندگان
چکیده
An N-terminal and C-terminal truncated recombinant α2-6-sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15-501)-His(6), was shown to be an efficient catalyst for one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 30 شماره
صفحات -
تاریخ انتشار 2011