Two-week, but not 1-week, hypoxic exposure enhances nitric oxide-mediated basal tone regulation in rat resistance pulmonary arteries.

نویسندگان

  • M Shirai
  • A Shimouchi
  • S Ikeda
  • H Oya
  • K Y Min
  • A T Kawaguchi
  • H Mori
  • I Ninomiya
چکیده

We measured internal diameter (ID) changes in resistance and conduit pulmonary arteries of 1- and 2-week hypoxic rats and normoxic control rats in response to nitric oxide synthase (NOS) inhibitors in vivo. At 2 weeks of hypoxic exposure, the ID reduction as a result of NOS inhibition was enhanced within the resistance arteries, but not at 1 week of hypoxia.

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عنوان ژورنال:
  • The Japanese journal of physiology

دوره 51 3  شماره 

صفحات  -

تاریخ انتشار 2001