The Overactive Bladder Controversies in the Pathophysiologic Basis of Unstable Detrusor Contraction

نویسنده

  • Marie Carmela Lapitan
چکیده

The concept of the overactive bladder was first introduced by Bates in the 1960’s as a description of an observation of the loss of the ability to inhibit normal detrusor activity (Bates 1971). Although emphasizing that the term did not imply a pathology, he acknowledged it to be of considerable importance in clinical practice, mainly because of its possible role as the cause of undesirable symptoms post surgery for incontinence.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In women with urinary incontinence how necessary is cystometry?

OBJECTIVES To evaluate the role of cystometry in the diagnostic evaluation of patients with symptoms of overactive bladder, by comparing the treatment outcome in those with and without urodynamically proven bladder instability. METHODS Prospective observational study performed at Urogynaecology Division, the Kidney Center Post-Graduate institute of nephro-urology, Karachi. Forty six patients ...

متن کامل

Antimuscarinic drugs in detrusor overactivity and the overactive bladder syndrome: motor or sensory actions?

Antimuscarinic drugs are generally thought to exert their therapeutic action on detrusor overactivity by reducing the ability of the detrusor muscle to contract. We review currently available published data to establish whether there is any evidence to support this contention. Using a PubMed data search, only 14 original articles (including two abstracts) were found that contained cystometric d...

متن کامل

سم بوتولینوم- A در درمان بی‌اختیاری ادراری ناشی از مثانه بیش‌فعال به دنبال ترومای نخاعی

Background: We evaluated the efficacy of botulinum-A toxin (BTX-A) injection into detrusor muscle in patients with incontinence resistant to anticholinergic drugs due to detrusor overactivity.Methods: Our prospective study included 12 male patients with detrusor overactivity and incontinence due to spinal cord injury, which had been unsuccessfully treated with anticholinergic medication. Under ...

متن کامل

The Effects of Acupuncture on Bladder Interstitial Cells of Cajal Excitability in Rats with Overactive Bladder

It is well known that acupuncture treatment has an effect on patients with an overactive bladder, but the mechanism of its action remains to be clarified. This study was aimed to investigate the effects of acupuncture on bladder overactivity, and the excitability of interstitial cells of Cajal of the bladder in a rat model of partial bladder outlet obstruction. Electroacupuncture (continuous wa...

متن کامل

P2X receptors and their role in female idiopathic detrusor instability.

PURPOSE It is clear from previous studies that adenosine triphosphate is released as a contractile co-transmitter with acetylcholine from parasympathetic nerves supplying the mammalian bladder but the physiological significance of ligand gated purinergic P2X receptors in human bladder innervation has not been adequately investigated. We examined the role of these receptors in female patients wi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011