Direct electrical single-molecule detection of DNA through electron transfer induced by hybridization.
نویسندگان
چکیده
Single-stranded DNA was utilized as a probe tip for single-molecule DNA detection. Hybridization of the DNA tip and target DNA induces electron tunneling through the resulting DNA duplex. It is demonstrated that the DNA tip allows not only genetic detection but also discovery of single-nucleotide polymorphisms at the single-molecule level.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 33 شماره
صفحات -
تاریخ انتشار 2013