Prediction of Protein-Protein Interaction Sites Using Support Vector Machines

Prediction of Protein Interaction Sites and Protein-Protein Interaction Pairs Using Support Vector Machines

Prediction of protein-protein interaction sites using support vector machines

The identification of protein-protein interaction sites is essential for the mutant design and prediction of protein-protein networks. The interaction sites of residue units were predicted using support vector machines (SVM) and the profiles of sequentially/spatially neighboring residues, plus additional information. When only sequence information was used, prediction performance was highest us...

A Comparative Study of Extreme Learning Machines and Support Vector Machines in Prediction of Sediment Transport in Open Channels

The limiting velocity in open channels to prevent long-term sedimentation is predicted in this paper using a powerful soft computing technique known as Extreme Learning Machines (ELM). The ELM is a single Layer Feed-forward Neural Network (SLFNN) with a high level of training speed. The dimensionless parameter of limiting velocity which is known as the densimetric Froude number (Fr) is predicte...

The identi®cation of protein±protein interaction sites is essential for the mutant design and prediction of protein± protein networks. The interaction sites of residue units

The identi®cation of protein±protein interaction sites is essential for the mutant design and prediction of protein± protein networks. The interaction sites of residue units were predicted using support vector machines (SVM) and the pro®les of sequentially/spatially neighboring residues, plus additional information. When only sequence information was used, prediction performance was highest usi...

Prediction of Protein-Protein Interaction Sites with Two-Stage Support Vector Machine

Protein-protein interactions play an important role in a number of biological processes such as DNA replication and repair, transcription, metabolism, and signal transduction cascade. To deeply understand protein-protein interactions, engineer proteins, and design drugs, we need to analyze detailed interaction mechanisms at the atomic level. Many protein complex structures have previously been ...