Pilot Study Using a Chitosan-Hydroxyapatite Implant for Guided Alveolar Bone Growth in Patients with Chronic Periodontitis
نویسندگان
چکیده
Periodontitis is an infectious and inflammatory disease associated with significant loss of alveolar crest and soft tissue attached to the teeth. Chitosan and hydroxyapatite are biomaterials used for bone tissue repair because of their biodegradability and biocompatibility in nature. The present study evaluated the effects of chitosan (CH) in combination with hydroxyapatite (HAP) to promote alveolar bone growth. A chitosan implant mixed with hydroxyapatite was implanted into the affected area of 9 patients suffering chronic periodontitis. Patients were evaluated through X-ray images and a millimetric slide over a one year period. The application of CH/HAP produced an average alveolar bone growth of 5.77 mm (±1.87 mm). At the onset of the study, the dental pocket exhibited a depth level (DPDL) of 8.66 mm and decreased to 3.55 mm one year after the implant. Tooth mobility grade was 2.44 mm at the onset and 0.8 mm at the end of the study with a significant difference of p < 0.001. Moreover, the bone density in the affected areas was similar to the density of the bone adjacent to it. This result was confirmed with the software implant viewer from Anne Solutions Company. In conclusion, the CH/HAP implant promoted alveolar bone growth in periodontitis patients.
منابع مشابه
Guided bone regeneration: A literature review
Guided bone regeneration (GBR) is a reconstructive procedure of alveolar ridge using membranes. This procedure is indicated when there is no sufficient bone for implantation, or in the case of optimal implant installation for esthetic or functional needs. GBR can be performed before implant placement, when there is not enough bone for initial stability of implants and less predictable outcomes ...
متن کاملComparison of the Effects of Local Injection and Oral Intake of Diclofenac and Atorvastatin in Alveolar Bone Density Assessed with CT in Experimental Periodontitis in Rat
Objectives The first cause of tooth loss in developed countries is periodontitis. Chronic periodontitis is the most common form of periodontitis and it is characterized by loss of periodontal attachment, destruction of alveolar bone and eventual loss of teeth. Atorvastatin is a statin drug used for the treatment of high cholesterol. Statins can stop the inflammatory proc...
متن کاملEvaluation of ocular hydroxyapatite implant with Tc-99m MDP bone scan [Persian]
Static bone scan was performed in 46 patients for evaluation of ocular Hydroxyapatite Vascularization. Study Findings indicated that bone scan, with TC-99m MDP is an appropriate method for evaluation of Hydroxyapatite Vascularization and for estimating the time For peg insertion into the Hydroxyapatite implant. Our study showed proper Hydroxyapatite Vascularization when the ratio of activ...
متن کاملHistological Comparison of Effectiveness of Low Doses of Doxycyclineand Atorvastatin on gingival Inflammation and Alveolar Bone Loss in Experimental Model of Periodontitis in Rats
Objectives: The purpose of this study was to evaluate the effect of low dose doxycycline and atorvastatin on gingival inflammation and alveolar bone loss in an experimental model of periodontitis in rats. Methods: Forty male Sprague Dawley rats were divided into four study groups as follows: (I) experimental periodontitis control, (II) rats with periodontitis treated with low dose atorvastatin...
متن کاملLateral alveolar ridge augmentation procedure using subperiosteal tunneling technique: a pilot study
Background: In this research article, we evaluate the use of sub-periosteal tunneling (tunnel technique) combined with alloplastic in situ hardening biphasic calcium phosphate (BCP, a compound of β-tricalcium phosphate and hydroxyapatite) bone graft for lateral augmentation of a deficient alveolar ridge. Methods: A total of 9 patients with deficient mandibular alveolar ridges were included in t...
متن کامل