Selective serotonin reuptake inhibitors and congenital malformations.
نویسنده
چکیده
منابع مشابه
Exposure to selective serotonin reuptake inhibitors and the risk of congenital malformations: a nationwide cohort study
OBJECTIVES To analyse the relation between selective serotonin reuptake inhibitor (SSRI) use and major congenital malformations, with focus on malformations of the heart. DESIGN Register-based retrospective nationwide cohort study, using the Danish Medical Birth Registry. SETTING Denmark. PARTICIPANTS Pregnant women in Denmark between 1997 and 2009 and their offspring. PRIMARY OUTCOME M...
متن کاملAntidepressant use during pregnancy and the risk of major congenital malformations in a cohort of depressed pregnant women: an updated analysis of the Quebec Pregnancy Cohort
OBJECTIVE Antidepressant use during gestation has been associated with risk of major congenital malformations but estimates can lack statistical power or be confounded by maternal depression. We aimed to determine the association between first-trimester exposure to antidepressants and the risk of major congenital malformations in a cohort of depressed/anxious women. SETTING AND PARTICIPANTS D...
متن کاملSelective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study
OBJECTIVE To investigate any association between selective serotonin reuptake inhibitors (SSRIs) taken during pregnancy and congenital major malformations. DESIGN Population based cohort study. PARTICIPANTS 493 113 children born in Denmark, 1996-2003. MAIN OUTCOME MEASURE Major malformations categorised according to Eurocat (European Surveillance of Congenital Anomalies) with additional d...
متن کاملSelective serotonin reuptake inhibitors in pregnancy and infant outcomes.
Adequate treatment of depression during pregnancy is very important for maternal, fetal and neonatal health. Selective serotonin reuptake inhibitors (SSRIs) are commonly used antidepressants. According to one American study, approximately 7% of pregnant women were prescribed an SSRI in 2004-2005. First trimester use of SSRIs, as a group, is unlikely to increase the risk of congenital malformati...
متن کاملUse of selective serotonin-reuptake inhibitors during early pregnancy and risk of congenital malformations: updated analysis
BACKGROUND Data on the safety of selective serotonin-reuptake inhibitors (SSRIs) in pregnancy are inconsistent. We examined associations between SSRI use during early pregnancy and risk of congenital malformations in infants. METHODS Set in Northern Denmark, our population-based prevalence study included 216,042 women who had a live birth after the 20th week of gestation. We compared the prev...
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ورودعنوان ژورنال:
- BMJ
دوره 339 شماره
صفحات -
تاریخ انتشار 2009