Clinical contribution of PET/CT in myeloma: from the perspective of a radiologist.

Title Clinical Contribution of PET/CT in Myeloma: From the Perspective of a Radiologist

False-positive FDG PET CT Scan in Vertebral Hemangioma

FDG PET CT scan is considered to be a sensitive tool to detect skeletal metastasis in known malignancies. However, it’s high sensitivity and low specificity may account for false positive diagnosis in cases of trauma, infection, inflammation and other benign conditions. Skeletal hemangioma is one of the common benign conditions which are typically ametabolic on FDG PET CT with no uptake on bone...

Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy

We studied 188 patients with a suspected smoldering multiple myeloma (MM) who had undergone a positron emission tomography-computed tomography (PET-CT) scan as part of their clinical evaluation. PET-CT was positive (clinical radiologist interpretation of increased bone uptake and/or evidence of lytic bone destruction) in 74 patients and negative in 114 patients. Of these, 25 patients with a pos...

Clinical Impact of 18F-FDG PET/CT on the Management of Gynecologic Cancers: One Center Experience

Objective(s): We aim to investigate the clinical impact of 18F-FDG PET/CT in managing patients with gynecological malignancies and pelvic or extrapelvic lymph nodes that are of equivocal significance on conventional imaging.Methods: We retrospectively evaluated 18F-FDG PET/CT scans of patients with gynecologic tumors who were referred to King Hussein Cancer Center from January 2010 to August 20...

Contribution of 68Ga-PSMA PET/CT to targeting volume delineation of prostate cancer treated with conformal radiation therapy: Which SUV threshold is appropriate?

Introduction: Prostate-specific membrane antigen (PSMA) has been demonstrated as a promising tool for specific imaging of prostate cancer (PCa) via positron emission tomography-computed tomography (PET/CT) scanning. Radiation treatment planning (RTP) based on 68Ga-PSMA PET/CT scanning can also lead to some decision modifications.  The specific goal o...