Vitamin D receptor activation: cardiovascular and renal implications

نویسندگان

  • Sagar U Nigwekar
  • Ravi Thadhani
چکیده

The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2013