The chaperone IpgC copurifies with the virulence regulator MxiE.
نویسندگان
چکیده
The expression of a subset of Shigella flexneri virulence genes is dependent upon a cytoplasmic chaperone, IpgC, and an activator from the AraC/XylS family, MxiE. In this paper, we report that the chaperone forms a specific and stable heteromer with MxiE.
منابع مشابه
Analysis of virulence plasmid gene expression defines three classes of effectors in the type III secretion system of Shigella flexneri.
Proteins directly involved in entry and dissemination of Shigella flexneri into epithelial cells are encoded by a virulence plasmid of 200 kb. A 30-kb region (designated the entry region) of this plasmid encodes components of a type III secretion (TTS) apparatus, substrates of this apparatus and their dedicated chaperones. During growth of bacteria in broth, expression of these genes is induced...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 190 6 شماره
صفحات -
تاریخ انتشار 2008