Transfer of myelogenous leukemia induced by gastric instillation of methylcholanthrene in Wistar rats.

نویسندگان

  • H SHAY
  • M GRUENSTEIN
  • C HARRIS
  • L GLAZER
چکیده

AND LILLIAN GLAZER S CASES of lymphatic and 2 of myelogenous leukemia developed in a group of random bred Wistar rats in which methylcholanthrene was itsstilled into the stomach.5 Attempts were made to transfer each type of leakemia to 30 to 40 clay old rats of our colony with only indifferent success in lymphatic leukemia and complete failure to achieve any transfers its myelogenous leukemia. Following the report of Gross,2 we used animals for transfer that were under 7 days of age and have been uniformly successful in transmitting the lymphatic leukemia to animals of our random bred Wistar colony.3 About a year ago another of our rats receiving methylcholanthrene by stomach catheter (Icveloped myelogenous leukemia. This has been transferred successfully to very young rats.

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عنوان ژورنال:
  • Blood

دوره 7 6  شماره 

صفحات  -

تاریخ انتشار 1952