Translational microsurgery. A new platform for transplantation research.

نویسندگان

  • Eiji Kobayashi
  • Junko Haga
چکیده

PURPOSE Clinical microsurgery has been introduced in many fields, while experimental microsurgery has the cross-disciplinary features of the sciences and techniques for growth of medicine, pharmacology, veterinary, engineering etc. Training protocol, proposing a new name as Translational Microsurgery, was introduced. METHODS Reconstructive skills of hepatic artery in pediatric living donor liver transplantation were summarized. Ex vivo training protocol using artificial blood vessel for surgeons was proposed. RESULTS Clinical microsurgery requires anastomosis with delicate arteries and limited field of view. Our training protocol revealed that the relation between the score and speed was seen, while not all the surgeons with enough experience got high score. This training led to muster clinical skills and to apply excellent experimental works. CONCLUSIONS Our microsurgical training protocol has been planned from the points of clinical setting. Training for vascular anastomosis led to rodent transplantation models. These models were used for immunology and immunosuppressant research. Microsurgical techniques led to master catheter technique and to inject various drugs or gene vectors.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Translational Insights on Lung Transplantation: Learning from Immunology

The introduction of ex vivo lung perfusion (EVLP) in the practice of lung transplantation has allowed the reconditioning of the marginal grafts and their conversion into transplantable grafts. In addition, EVLP can provide a platform for the application of various preventive measures to decrease the incidence of post-transplant complications. While the Toronto team targets the attenuation of th...

متن کامل

Robot-Assisted Pterygium Surgery: Feasibility Study in a Nonliving Porcine Model.

PURPOSE This study aims to investigate the feasibility of pterygium surgery using the DaVinci Si HD robotic surgical system, and to describe a porcine model for pterygium surgery and evaluate its usefulness. METHODS The pterygium models were constructed using enucleated pig eyes and cold cuts. Robotically-assisted pterygium surgeries in nonliving biological pterygium models were performed usi...

متن کامل

Composite tissue allotransplantation.

Composite tissue allotransplantation (CTA) recently took its first steps in the clinical arena in 1998 with the successful hand transplant performed in Lyons, France. That single operation represented a culmination of many years of laboratory research in multiple fields involving integumentary/musculoskeletal transplantation. Here we review the prerequisite developments in the field of immunolo...

متن کامل

The contribution of experimental microsurgery to medicine development: The history of world-first agonist medicine development with S1P receptor functions

Prologue The role of academia in terms of developing medicine in our country is highly advanced. However, the academia-industry infrastructural improvement for clinical development has not reached to some extent; world-class. I have been involved in the research for new and innovative immunosuppressive agent for a long time thanks to the fact that I have extended research method of preclinical ...

متن کامل

Composite Tissue Transplantation: A New Era in Transplantation Surgery

Once belonging to science fiction, face transplantation is a clinical reality now. The controversial first face transplantation in Amiens, France in 2005 was followed by significant ethical debate among physicians, surgeons, scientists and bioethicists. The controversies are being followed by cautious optimism and acceptance. An increasing number of surgical teams are developing protocols of co...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Acta cirurgica brasileira

دوره 31 3  شماره 

صفحات  -

تاریخ انتشار 2016